There are many kinds of nutritional supplements that increase serotonin levels — amino acids, vitamins, minerals, herbs, and more.
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Selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, Zoloft, Celexa, and Lexapro are used by millions to relieve symptoms of depression by increasing brain levels of serotonin.
But SSRIs can have serious side effects and don’t work for everyone, possibly up to 40 percent of those who try them (1).
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Some research shows they work no better than a placebo (2).
Several other brain-related disorders besides depression are related to low serotonin, including autism, ADHD, bipolar disorder, sleep disorders, and schizophrenia (3).